Via John MacArthur,
'...Part of the process of true mortification or the killing of sin is working through the issue of guilt. If you want to know where in your life sin hasn't been dealt with, just listen to your conscience. That's very contrary, by the way, to the popular wisdom of our day. The popular wisdom of our day is very different. Listen to what John Owen wrote, "If you want to kill sin, load your conscience with the guilt of it." Wow! Most people today would tell you to run from guilt. John Owen said load your conscience with guilt. He believed the pangs of guilt were a natural and healthy consequence of wrong doing. Be ashamed, he wrote, be greatly ashamed for he saw shame as an advantage....'
Sourced from John Owen's Mortifying Sin:
'...Load your conscience with the guilt of it. Not only
consider that it has a guilt, but load your conscience with the guilt of its actual
eruptions and disturbances...'