For flights
http://www.airfarewatchdog.com
It allows a price search to anywhere from a chosen destination.
http://www.skyscanner.com
Another good flight fare resource with similar features.
The cheapest fair I've seen is $53 per person round trip between NYC and Cape Code (HYA).
For cruise, there are plenty. Cruise to Nowhere is a keyword for destination that is at sea. Usually people do it for cruising testing, casino or duty free reasons. Rate is around $180 per person.